Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.50 |
| ▸ | NQO2 | P16083 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885914 | 0.84 | MTNR1A (0.64) | MTNR1ANQO2MTNR1B | |
| SCHEMBL8883881 | 0.84 | MTNR1A (0.69) | MTNR1ANQO2MTNR1BMEN1KMT2A | |
| SCHEMBL8619791 | 0.84 | MTNR1A (0.72) | MTNR1ANQO2MTNR1B | |
| SCHEMBL8883232 | 0.82 | EPHX1 (0.52) | MTNR1ANQO2MTNR1BMEN1KMT2A | |
| SCHEMBL27450734 | 0.80 | MTNR1A (0.70) | MTNR1ANQO2MTNR1B | |
| SCHEMBL8885911 | 0.80 | MTNR1A (0.70) | MTNR1ANQO2MTNR1B | |
| SCHEMBL8886521 | 0.78 | HTR1D (0.50) | MTNR1AMTNR1B | |
| SCHEMBL8884628 | 0.78 | EPHX1 (0.53) | MTNR1ANQO2MTNR1BMEN1KMT2A | |
| SCHEMBL8886732 | 0.77 | NCEH1 (0.42) | MTNR1ANQO2MTNR1BMEN1KMT2A | |
| SCHEMBL3238625 | 0.73 | CYP1A2 (0.55) | MTNR1AMTNR1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612368-A | SKIN DISORDERS, MELATONINERGIC SYSTEMS, ANTIARRHYTHMIA AGENTS OR ANTIISCHEMIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-03-18 | — | — | US | disclosed |