Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | PGD | P52209 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20798105 | 0.97 | TSHR (0.50) | TSHRPGDFOLH1PGK1PGK2 | |
| SCHEMBL27481 | 0.97 | TSHR (0.50) | TSHRPGDFOLH1PGK1PGK2 | |
| SCHEMBL16058860 | 0.94 | TSHR (0.47) | TSHRPGDFOLH1PGK1PGK2 | |
| Water SCHEMBL5002268 | 0.94 | TSHR (0.47) | TSHRPGDFOLH1PGK1PGK2 | |
| Glycerin SCHEMBL22285861 | 0.84 | PDE4A (0.40) | TSHRPGDFOLH1PGK1PGK2 | |
| SCHEMBL20475911 | 0.79 | PDE4A (0.44) | TSHRPGDFOLH1PGK1PGK2 | |
| SCHEMBL917799 | 0.77 | PDE4A (0.43) | TSHRPGDFOLH1PGK1PGK2 | |
| SCHEMBL1533815 | 0.76 | TSHR (0.32) | TSHRPGDMEN1LMNAHPGD | |
| SCHEMBL20493915 | 0.76 | LMNA (0.33) | TSHRPGDMEN1LMNAHPGD | |
| SCHEMBL8104683 | 0.76 | LMNA (0.33) | TSHRPGDMEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665802-A | REACTING POLYAMIC ACID WITH A DEHYDRATION-CYCLIZATION AGENT, A CATALYST AND AN ORGANIC PHOSPHORUS COMPOUND; EXCELLENT IN TENSILE STRENGTH AND FLEXIBILITY | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-09-09 | — | — | US | claimed |
| US-5665802-A | REACTING POLYAMIC ACID WITH A DEHYDRATION-CYCLIZATION AGENT, A CATALYST AND AN ORGANIC PHOSPHORUS COMPOUND; EXCELLENT IN TENSILE STRENGTH AND FLEXIBILITY | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0350958-B1 | Improved polyimide and polyimide film and manufacturing method thereof | KANEGAFUCHI CHEMICAL IND (JP) | 1994-12-21 | — | — | EP | disclosed |
| EP-0350958-A2 | Improved polyimide and polyimide film and manufacturing method thereof | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-17 | — | — | EP | disclosed |