SCHEMBL888487

SCHEMBL888487

CCOC(=O)C(COC)(CC(C)C)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.46
PKM P14618 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 2/20 0.31
CYP4F2 P78329 2/20 0.31
CYP4A11 Q02928 2/20 0.31
THRB P10828 1/20 0.31
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30
HTT P42858 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888495 0.86 MMP8 (0.46) MMP8PKMKDM4EMEN1KMT2A
SCHEMBL8161089 0.86 MMP8 (0.38) MMP8PKMKDM4EMEN1KMT2A
SCHEMBL888526 0.84 MMP8 (0.35) MMP8
SCHEMBL6343592 0.83 MMP8 (0.37) MMP8PKMKDM4EMEN1KMT2A
SCHEMBL15243249 0.81 MMP8 (0.47) MMP8PKMKDM4EMEN1KMT2A
SCHEMBL820209 0.79 MMP8 (0.49) MMP8PKMKDM4EMEN1KMT2A
SCHEMBL14890726 0.79 MMP8 (0.49) MMP8PKMKDM4EMEN1KMT2A
SCHEMBL8154123 0.77 CYP3A4 (0.47) MMP8ALDH1A1LMNAHSD17B10
SCHEMBL818899 0.77
SCHEMBL17617114 0.75 MMP8 (0.43) MMP8PKMKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed
EP-1141044-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER Basell Technology Company B.V. (NL) 2001-10-10 EP disclosed
WO-2001036496-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-05-25 WO disclosed
US-6121483-A 3-alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin SHOWA DENKO K.K. (JP) 2000-09-19 US disclosed
US-6118019-A 3-alkoxypropionic ester derivative SHOWA DENKO K.K. (JP) 2000-09-12 US disclosed
US-6015867-A MIXTURES OF ORGANOALUMINUM COMPOUNDS, MAGNESIUM, TITANIUM AND HALOGEN COMPOUNDS WITH ELECTRON DONOR ESTER AS INTENSIFIER, NONTOXIC, SAFE, EFFICIENT SHOWA DENKO K.K. (JP) 2000-01-18 US disclosed
EP-0704424-B1 3-Alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin SHOWA DENKO KK (JP) 1998-12-30 EP disclosed
EP-0704424-A1 3-alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin SHOWA DENKO KABUSHIKI KAISHA (JP) 1996-04-03 EP disclosed