Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 3/20 | 0.43 |
| ▸ | FABP3 | P05413 | 2/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915884 | 0.80 | GABRA1 (0.48) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL31502507 | 0.80 | GABRA1 (0.48) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL8884997 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL21415476 | 0.76 | GABRA1 (0.45) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL6063410 | 0.76 | GABRA1 (0.45) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL17125433 | 0.76 | GABRA1 (0.50) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL28111265 | 0.76 | GABRA1 (0.45) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL31114144 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL7064227 | 0.74 | GABRA1 (0.43) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL3192221 | 0.74 | GABRA1 (0.43) | GABRA1GABRB2FABP4FABP3FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616601-A | 1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation | GD SEARLE & CO (US) | 1997-04-01 | — | — | US | claimed |
| US-5616601-A | 1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation | GD SEARLE & CO (US) | 1997-04-01 | — | — | US | disclosed |