Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863339 | 1.00 | ITGB3 (0.53) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7276132 | 1.00 | ITGB3 (0.53) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7275741 | 0.92 | ITGB3 (0.55) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7275275 | 0.90 | ITGB3 (0.43) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7275855 | 0.89 | ITGB3 (0.44) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7283387 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7285442 | 0.89 | ITGB3 (0.52) | ITGB3ITGA2BPRSS1 | |
| SCHEMBL7283158 | 0.88 | ITGB3 (0.50) | ITGB3ITGA2BNQO2 | |
| SCHEMBL7283070 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Water SCHEMBL7276158 | 0.87 | ITGB3 (0.53) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | claimed |