Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.38 |
| ▸ | TACR2 | P21452 | 5/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885666 | 1.00 | TACR1 (0.38) | TACR1TACR2OPRK1 | |
| SCHEMBL7954472 | 0.73 | UTS2R (0.48) | TACR1TACR2OPRK1 | |
| SCHEMBL29790470 | 0.70 | PPARA (0.54) | TACR1TACR2 | |
| SCHEMBL8882429 | 0.70 | TACR2 (0.65) | TACR1TACR2 | |
| SCHEMBL8883479 | 0.70 | TACR2 (0.65) | TACR1TACR2 | |
| SCHEMBL8592345 | 0.70 | TACR2 (0.65) | TACR1TACR2 | |
| SCHEMBL9028189 | 0.69 | TACR2 (0.60) | TACR1TACR2 | |
| SCHEMBL9027911 | 0.69 | TACR2 (0.60) | TACR1TACR2 | |
| SCHEMBL8366587 | 0.69 | TACR2 (0.60) | TACR1TACR2 | |
| SCHEMBL8953928 | 0.68 | TACR1 (0.59) | TACR1TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607947-A | Pyrrolidinyl tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-03-04 | — | — | US | disclosed |