Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592265 | 0.83 | UTS2R (0.50) | UTS2RTACR1OPRK1TACR2CYP3A4 | |
| SCHEMBL8806880 | 0.81 | TACR1 (0.44) | TACR1TACR2 | |
| SCHEMBL7954954 | 0.80 | OPRK1 (0.42) | TACR1OPRK1CYP3A4CYP2D6 | |
| SCHEMBL8592264 | 0.77 | TACR1 (0.44) | UTS2RTACR1OPRK1TACR2 | |
| SCHEMBL29790470 | 0.76 | PPARA (0.54) | TACR1TACR2 | |
| SCHEMBL8302191 | 0.74 | POLB (0.51) | — | |
| SCHEMBL8885666 | 0.73 | TACR1 (0.38) | TACR1OPRK1TACR2 | |
| SCHEMBL8885672 | 0.73 | TACR1 (0.38) | TACR1OPRK1TACR2 | |
| SCHEMBL7956616 | 0.72 | TACR2 (0.44) | UTS2RTACR1TACR2CYP3A4 | |
| SCHEMBL8308100 | 0.70 | TACR1 (0.61) | TACR1TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |