SCHEMBL888639

SCHEMBL888639

CCOCC(CC(C)C)(C(=O)OCC)C(C)(C)CC

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 2/20 0.46
CYP4F2 P78329 3/20 0.32
CYP4A11 Q02928 3/20 0.32
MAPT P10636 1/20 0.31
PIN1 Q13526 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888359 0.88 MMP8 (0.46) MMP8CYP4F2CYP4A11MAPTPIN1
SCHEMBL888403 0.87 MMP8 (0.49) MMP8CYP4F2CYP4A11MAPTPIN1
SCHEMBL819127 0.83 MMP8 (0.34) MMP8
SCHEMBL28849108 0.78 MMP8 (0.51) MMP8CYP4F2CYP4A11MAPTPIN1
SCHEMBL888396 0.76 CYP4F2 (0.37) MMP8CYP4F2CYP4A11PIN1PKM
SCHEMBL12549769 0.75 MMP8 (0.53) MMP8CYP4F2CYP4A11MAPTPIN1
SCHEMBL819850 0.75 MMP8 (0.49) MMP8CYP4F2CYP4A11MAPTPIN1
SCHEMBL888428 0.74 MMP8 (0.49) MMP8CYP4F2CYP4A11MAPTPIN1
SCHEMBL888356 0.74 MMP8 (0.38) MMP8CYP4F2CYP4A11PKM
SCHEMBL888557 0.74 MMP8 (0.38) MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed