Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.72 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.64 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593914 | 0.84 | PTGS2 (0.74) | PTGS2GABRA2GABRB2PTGS1 | |
| SCHEMBL5594360 | 0.84 | PTGS2 (0.74) | PTGS2GABRA2GABRB2PTGS1 | |
| SCHEMBL6390052 | 0.84 | PTGS2 (0.74) | PTGS2GABRA2GABRB2PTGS1 | |
| SCHEMBL5594254 | 0.84 | PTGS2 (0.68) | PTGS2GABRA2GABRB2PTGS1 | |
| SCHEMBL5594811 | 0.84 | PTGS2 (1.00) | PTGS2GABRA2GABRB2PTGS1 | |
| SCHEMBL6393310 | 0.83 | PTGS2 (0.72) | PTGS2GABRA2GABRB2PTGS1 | |
| SCHEMBL5594144 | 0.83 | PTGS2 (0.72) | PTGS2GABRA2GABRB2PTGS1 | |
| SCHEMBL8884720 | 0.82 | PTGS2 (0.71) | PTGS2GABRA2GABRB2PTGS1 | |
| SCHEMBL5594103 | 0.81 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL5594722 | 0.81 | PTGS2 (0.80) | PTGS2GABRA2GABRB2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616601-A | 1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation | GD SEARLE & CO (US) | 1997-04-01 | — | — | US | disclosed |