Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888631 | 0.95 | ADORA2A (0.37) | ADORA2AADORA1ADORA2BNPSR1RXFP1 | |
| SCHEMBL8889030 | 0.86 | PTGER1 (0.40) | NPSR1KDM4EHPGDALDH1A1PTGER1 | |
| SCHEMBL8888287 | 0.84 | RIPK2 (0.40) | ADORA1NPSR1RXFP1KDM4EHPGD | |
| SCHEMBL8889197 | 0.84 | IDO1 (0.39) | ADORA2AADORA1ADORA2BNPSR1KDM4E | |
| SCHEMBL8887358 | 0.82 | IDO1 (0.39) | ADORA2AADORA1ADORA2BNPSR1KDM4E | |
| SCHEMBL8888315 | 0.81 | KIF11 (0.36) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL8890875 | 0.81 | ADORA2A (0.43) | ADORA2AADORA1ADORA2BDPP4MAPK13 | |
| SCHEMBL8889425 | 0.81 | RIPK2 (0.37) | ADORA1NPSR1KDM4EMAPK13RAF1 | |
| SCHEMBL8888763 | 0.80 | ADORA1 (0.37) | ADORA2AADORA1ADORA2BNPSR1KDM4E | |
| SCHEMBL8890471 | 0.79 | RIPK2 (0.38) | ADORA1NPSR1KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |