Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.66 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594811 | 0.79 | PTGS2 (1.00) | PTGS2GABRA2GABRB2 | |
| SCHEMBL5594813 | 0.79 | PTGS2 (0.55) | PTGS2 | |
| SCHEMBL5594725 | 0.78 | PTGS2 (0.55) | PTGS2 | |
| SCHEMBL5594133 | 0.78 | PTGS2 (0.55) | PTGS2 | |
| SCHEMBL6332827 | 0.77 | CNR1 (0.53) | GABRA2GABRB2CHRNA7 | |
| SCHEMBL8884924 | 0.73 | PTGS2 (0.60) | PTGS2 | |
| SCHEMBL8422289 | 0.73 | PTGS2 (0.57) | PTGS2CA9CA1CA2CA4 | |
| SCHEMBL3024651 | 0.72 | CHRNA7 (0.60) | PTGS2CA9CA1CA2CA4 | |
| SCHEMBL4510377 | 0.72 | CNR1 (0.55) | GABRA2GABRB2 | |
| SCHEMBL8423687 | 0.71 | PTGS2 (0.66) | PTGS2CA9CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616601-A | 1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation | GD SEARLE & CO (US) | 1997-04-01 | — | — | US | disclosed |