Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9078640 | 0.82 | — | — | |
| SCHEMBL6660780 | 0.79 | TRPA1 (0.37) | TRPA1 | |
| SCHEMBL6660790 | 0.79 | TRPA1 (0.37) | TRPA1 | |
| SCHEMBL7873198 | 0.76 | — | — | |
| SCHEMBL702655 | 0.72 | PRSS1 (0.33) | — | |
| SCHEMBL706845 | 0.72 | KCNH2 (0.33) | TRPA1 | |
| SCHEMBL7494988 | 0.72 | — | — | |
| SCHEMBL28550618 | 0.71 | CYP24A1 (0.31) | — | |
| SCHEMBL28549733 | 0.70 | MEN1 (0.30) | — | |
| SCHEMBL2008257 | 0.70 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621098-A | ALKYLATION OF THE CORRESPONDING BISINDOLE COMPOUND; CYCLIZATION; PROTEIN C KINEASE INHIBITOR | ELI LILLY AND COMPANY (US) | 1997-04-15 | — | — | US | disclosed |