Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024403 | 0.95 | LMNA (0.57) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL8888171 | 0.91 | LMNA (0.56) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL7803388 | 0.90 | LMNA (0.54) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL18633373 | 0.88 | LMNA (0.68) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL1031729 | 0.82 | LMNA (0.71) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL28927348 | 0.82 | LMNA (0.76) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Hydrochloric Acid SCHEMBL12005237 | 0.81 | LMNA (0.69) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Hydrochloric Acid SCHEMBL12004704 | 0.81 | LMNA (0.69) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL8887038 | 0.81 | LMNA (0.58) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Hydrochloric Acid SCHEMBL6041931 | 0.79 | LMNA (0.68) | LMNAMAPK1ALDH1A1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700825-A | USED TO KILL HYPOXIC TUMOR CELLS | FLORIDA STATE UNIVERSITY (US) | 1997-12-23 | — | — | US | disclosed |