Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594587 | 0.92 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594817 | 0.92 | PTGS2 (0.86) | PTGS2PTGS1 | |
| SCHEMBL5594149 | 0.89 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL5595179 | 0.87 | PTGS2 (0.84) | PTGS2PTGS1 | |
| SCHEMBL5593898 | 0.87 | PTGS2 (0.83) | PTGS2PTGS1 | |
| SCHEMBL5594528 | 0.87 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL212940 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594495 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594654 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594119 | 0.83 | PTGS2 (0.77) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616601-A | 1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation | GD SEARLE & CO (US) | 1997-04-01 | — | — | US | claimed |