Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.56 |
| ▸ | FUCA1 | P04066 | 8/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 6/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25590460 | 0.98 | S1PR1 (0.55) | S1PR1S1PR3FUCA1HTR1AGBA1 | |
| SCHEMBL25590455 | 0.98 | S1PR1 (0.55) | S1PR1S1PR3FUCA1HTR1AGBA1 | |
| SCHEMBL25590453 | 0.98 | S1PR1 (0.55) | S1PR1S1PR3FUCA1HTR1AGBA1 | |
| SCHEMBL28832843 | 0.98 | S1PR1 (0.54) | S1PR1S1PR3FUCA1HTR1AGBA1 | |
| SCHEMBL9740250 | 0.92 | HTR1A (0.51) | S1PR1S1PR3FUCA1HTR1AGBA1 | |
| SCHEMBL23471349 | 0.89 | FUCA1 (0.49) | S1PR1S1PR3FUCA1HTR1AGBA1 | |
| SCHEMBL16511592 | 0.89 | FUCA1 (0.49) | S1PR1S1PR3FUCA1HTR1AGBA1 | |
| SCHEMBL8580603 | 0.86 | S1PR1 (0.60) | S1PR1S1PR3FUCA1GBA1NAAA | |
| SCHEMBL6278007 | 0.86 | S1PR1 (0.60) | S1PR1S1PR3FUCA1GBA1NAAA | |
| SCHEMBL1931621 | 0.86 | S1PR1 (0.60) | S1PR1S1PR3FUCA1GBA1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621103-A | 3-(SUBSTITUTED METHYLAMINOCARBONYL)-1,2,3,4-TETRAHYDRO-(1)BENZOTHIENO(2,3-C) PYRIDINES; ANXIOLYTIC AGENTS; LEARNING ENHANCEMENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-04-15 | — | — | US | disclosed |