Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894662 | 0.84 | NEU3 (0.50) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5686135 | 0.83 | KMT2A (0.58) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5682853 | 0.83 | KMT2A (0.61) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6082044 | 0.80 | ALDH1A1 (0.45) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29022766 | 0.80 | KDM4E (0.51) | KMT2AALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL1515872 | 0.80 | CA12 (0.62) | ALDH1A1KDM4EPOLBCA12CA1 | |
| SCHEMBL5682954 | 0.79 | KMT2A (0.67) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11617743 | 0.79 | KMT2A (0.56) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31375393 | 0.78 | KMT2A (0.65) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29097191 | 0.78 | KMT2A (0.65) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602277-A | Substituted benzene derivatives useful as neuraminidase inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996030329-A1 | SUBSTITUTED BENZENE DERIVATIVES USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INCORPORATED (US) | 1996-10-03 | — | — | WO | disclosed |