Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.74 |
| ▸ | CA9 | Q16790 | 6/20 | 0.74 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884828 | 0.99 | CA12 (0.72) | CA12CA9LPAR2CA1CA2 | |
| SCHEMBL8885028 | 0.95 | CA12 (0.74) | CA12CA9LPAR2CA1CA2 | |
| SCHEMBL3336990 | 0.85 | CA12 (1.00) | CA12CA9LPAR2CA1CA2 | |
| SCHEMBL10766816 | 0.84 | CA12 (0.97) | CA12CA9LPAR2CA1CA2 | |
| SCHEMBL9490703 | 0.84 | CA12 (0.97) | CA12CA9LPAR2CA1CA2 | |
| SCHEMBL9490269 | 0.84 | CA12 (0.97) | CA12CA9LPAR2CA1CA2 | |
| SCHEMBL1924309 | 0.80 | CA12 (0.72) | CA12CA9LPAR2CA1CA2 | |
| SCHEMBL13320282 | 0.78 | CA12 (0.79) | CA12CA9LPAR2CA1CA2 | |
| SCHEMBL26212219 | 0.77 | CA12 (0.71) | CA12CA9LPAR2CA1CA2 | |
| SCHEMBL1923940 | 0.77 | CA12 (0.71) | CA12CA9LPAR2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046525-A1 | 5-ALKOXY-TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS 5-HT1D RECEPTOR AGONISTS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-12-11 | — | — | WO | disclosed |
| US-5654431-A | EXHIBIT SELECTIVITY TOWARDS 5-HYDROXYTRYPTAMINE RECEPTORS OF BRAIN CELLS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-08-05 | — | — | US | disclosed |