Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 1.00 |
| ▸ | CA9 | Q16790 | 6/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10766816 | 0.99 | CA12 (0.97) | CA12CA9RECQLLPAR2CA1 | |
| SCHEMBL9490703 | 0.99 | CA12 (0.97) | CA12CA9RECQLLPAR2CA1 | |
| SCHEMBL9490269 | 0.99 | CA12 (0.97) | CA12CA9RECQLLPAR2CA1 | |
| SCHEMBL617098 | 0.88 | CA12 (0.79) | CA12CA9RECQLLPAR2MEN1 | |
| SCHEMBL23748667 | 0.87 | CA12 (0.78) | CA12CA9RECQLLPAR2MEN1 | |
| SCHEMBL11799407 | 0.86 | CA12 (0.75) | CA12CA9RECQLLPAR2CA1 | |
| SCHEMBL8887751 | 0.85 | CA12 (0.74) | CA12CA9RECQLLPAR2CA1 | |
| SCHEMBL13320282 | 0.84 | CA12 (0.79) | CA12CA9LPAR2CA1CA2 | |
| SCHEMBL8884828 | 0.84 | CA12 (0.72) | CA12CA9RECQLLPAR2CA1 | |
| SCHEMBL8885028 | 0.84 | CA12 (0.74) | CA12CA9RECQLLPAR2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119699-B1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | BAYER IP GMBH (DE) | 2016-09-21 | — | — | EP | disclosed |
| US-8236986-B2 | Process for preparing acylsulfamoylbenzamides | BAYER CROPSCIENCE GMBH (DE) | 2012-08-07 | — | — | US | disclosed |
| US-20100094052-A1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | BAYER CROPSCIENCE GMBH (DE) | 2010-04-15 | — | — | US | disclosed |
| EP-2119699-A1 | Process for preparing acylsulfamoylbenzamides | Bayer CropScience AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| US-7608736-B2 | Chlorination a a benzenesulfamoyl compound in presence of a base | BAYER CROPSCIENCE GMBH (DE) | 2009-10-27 | — | — | US | disclosed |
| EP-1644324-B1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | BAYER CROPSCIENCE AG (DE) | 2009-09-30 | — | — | EP | disclosed |
| EP-1644324-A1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | Bayer CropScience GmbH (DE) | 2006-04-12 | — | — | EP | disclosed |
| US-20050004372-A1 | Process for preparing acylsulfamoylbenzamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | US | disclosed |
| WO-2005000797-A1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | BAYER CROPSCIENCE GMBH (DE) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094052-A1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | SULT2A1, STS, SULT1A1 | CA12 502/4885CA9 368/4885RECQL 3086/4885 |
| US-20050004372-A1 | Process for preparing acylsulfamoylbenzamides | SULT2A1, STS, SULT1A1 | CA12 502/4885CA9 368/4885RECQL 3086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.