⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL951290 | 0.88 | — | — | |
| SCHEMBL10978922 | 0.87 | — | — | |
| SCHEMBL8885600 | 0.83 | — | — | |
| SCHEMBL8885590 | 0.83 | — | — | |
| SCHEMBL8885594 | 0.83 | — | — | |
| SCHEMBL8887799 | 0.82 | TAAR1 (0.47) | — | |
| Alcohol SCHEMBL8886186 | 0.82 | — | — | |
| SCHEMBL8887574 | 0.81 | — | — | |
| SCHEMBL8887566 | 0.81 | — | — | |
| SCHEMBL8887562 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643784-A | TREATMENT OF ANXIETY, DEPRESSION, SLEEPING DISORDERS, SCHIZOPHRENIA AND MIGRAINE | H, LUNDBECK A/S (DK) | 1997-07-01 | — | — | US | disclosed |
| EP-0560868-B1 | INDAN DERIVATIVES | LUNDBECK & CO AS H (DK) | 1995-04-19 | — | — | EP | disclosed |
| EP-0560868-A1 | INDAN DERIVATIVES. | LUNDBECK & CO AS H (DK) | 1993-09-22 | — | — | EP | disclosed |
| WO-1992010192-A1 | INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 1992-06-25 | — | — | WO | disclosed |
| EP-0183349-B1 | INDANE DERIVATIVES AND METHODS OF PREPARATION AND TREATMENT | H. LUNDBECK A/S (DK) | 1990-10-03 | — | — | EP | disclosed |
| US-4684650-A | CARDIOVASCULAR DISORDERS | H. LUNDBECK A/S (DK) | 1987-08-04 | — | — | US | disclosed |
| EP-0183349-A1 | Indane derivatives and methods of preparation and treatment | H. LUNDBECK A/S (DK) | 1986-06-04 | — | — | EP | disclosed |