SCHEMBL8887799

SCHEMBL8887799

Fc1ccccc1C1CC(N2CCNCC2)c2ccccc21

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.47
KDM1A O60341 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8887801 0.82
SCHEMBL951290 0.81
SCHEMBL6001957 0.72
SCHEMBL6001952 0.72
SCHEMBL10978922 0.70
SCHEMBL30660225 0.68 TAAR1 (0.41) TAAR1
SCHEMBL11034439 0.67 HTR2C (0.49) TAAR1
SCHEMBL7446797 0.67 HTR2C (0.49) TAAR1KDM1A
SCHEMBL10671994 0.67 TAAR1 (0.54) TAAR1
SCHEMBL10704866 0.67 TAAR1 (0.54) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5643784-A TREATMENT OF ANXIETY, DEPRESSION, SLEEPING DISORDERS, SCHIZOPHRENIA AND MIGRAINE H, LUNDBECK A/S (DK) 1997-07-01 US disclosed
EP-0560868-B1 INDAN DERIVATIVES LUNDBECK & CO AS H (DK) 1995-04-19 EP disclosed
EP-0560868-A1 INDAN DERIVATIVES. LUNDBECK & CO AS H (DK) 1993-09-22 EP disclosed
WO-1992010192-A1 INDAN DERIVATIVES H. LUNDBECK A/S (DK) 1992-06-25 WO disclosed