Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10071035 | 0.76 | — | — | |
| SCHEMBL15116489 | 0.72 | — | — | |
| SCHEMBL10999225 | 0.72 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TDP1GAA | |
| SCHEMBL17487351 | 0.70 | — | — | |
| SCHEMBL28906642 | 0.69 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| Acetone SCHEMBL28323239 | 0.69 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10TDP1GAA | |
| Acetone SCHEMBL3131149 | 0.69 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10TDP1GAA | |
| Acetic Acid SCHEMBL9771962 | 0.69 | FFAR3 (0.41) | ALDH1A1LMNAHSD17B10TDP1GAA | |
| SCHEMBL7276742 | 0.69 | FFAR3 (0.36) | ALDH1A1LMNAHSD17B10TDP1GAA | |
| SCHEMBL28476006 | 0.69 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631264-A | NEUROLOGICAL DISORDERS | SANOFI WINTHROP, INC. (US) | 1997-05-20 | — | — | US | disclosed |
| US-5554620-A | Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof | STERLING WINTHROP INC. (US) | 1996-09-10 | — | — | US | disclosed |
| EP-0656359-A1 | Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts and compositionsand methods of use thereof | STERLING WINTHROP INC. (US) | 1995-06-07 | — | — | EP | disclosed |