Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.49 |
| ▸ | ABAT | P80404 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145513 | 0.94 | ALDH1A1 (0.62) | ALDH1A1TSHRHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL14387566 | 0.84 | TUBB1 (0.55) | — | |
| SCHEMBL2001921 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TSHRHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL17396312 | 0.83 | ALDH1A1 (0.47) | ALDH1A1TSHRHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL17318087 | 0.83 | ALDH1A1 (0.68) | ALDH1A1TSHRHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL9958281 | 0.82 | ALDH1A1 (0.72) | ALDH1A1TSHRHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL2004462 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL1786055 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHRHPGDSMN1; SMN2FDPS | |
| SCHEMBL147333 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TSHRHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL2001231 | 0.81 | GAA (0.53) | ALDH1A1TSHRHPGDFDPSTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |