Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 7/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890308 | 0.90 | CCNB2 (0.40) | MAPTSMN1; SMN2L3MBTL1MAOBMAOA | |
| SCHEMBL8887456 | 0.89 | NPC1 (0.42) | HPGDSMN1; SMN2MAOBNPC1RAB9A | |
| SCHEMBL8888740 | 0.87 | APP (0.39) | MAPTL3MBTL1MAOBRAB9ARXRA | |
| SCHEMBL7156085 | 0.80 | RXRA (0.48) | LMNARXRAHNF4A | |
| SCHEMBL727912 | 0.78 | RXRA (0.46) | RXRAHNF4A | |
| SCHEMBL6915771 | 0.77 | MAOB (0.49) | MAPTSMN1; SMN2L3MBTL1MAOBMAOA | |
| SCHEMBL6017468 | 0.77 | RXRA (0.43) | RXRAGNRHRHNF4A | |
| SCHEMBL8890044 | 0.76 | RXRA (0.35) | MAPTALDH1A1RXRACYP3A4HNF4A | |
| SCHEMBL8889198 | 0.75 | RXRA (0.46) | RXRAHNF4A | |
| SCHEMBL8889384 | 0.74 | RXRA (0.47) | RXRAHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997012853-A1 | DIMER-SELECTIVE RXR MODULATORS AND METHODS FOR THEIR USE | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-04-10 | — | — | WO | disclosed |