Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765076 | 0.83 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL1697354 | 0.82 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL1518200 | 0.82 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL30356274 | 0.77 | — | — | |
| SCHEMBL9337819 | 0.76 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL526662 | 0.76 | SMN1; SMN2 (0.58) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL8540804 | 0.76 | CES1 (0.42) | RAB9AHTTCES1 | |
| SCHEMBL22952562 | 0.76 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL80996 | 0.74 | — | — | |
| SCHEMBL27827575 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599948-A | Substituted dipyrromethanes and their preparation | SUN COMPANY, INC. (US) | 1997-02-04 | — | — | US | disclosed |
| US-5536844-A | Substituted dipyrromethanes and their preparation | SUNCOMPANY, INC. (R&M) (US) | 1996-07-16 | — | — | US | disclosed |
| US-5502211-A | Substituted dipyrromethanes and their preparation | SUN COMPANY, INC. (R&M) (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0655438-A2 | Bis (pyrrol-2-yl)halocarbylmethanes and processes for their preparation | SUN COMPANY, INC. (R&M) (US) | 1995-05-31 | — | — | EP | disclosed |
| US-4315020-A | Oxazoline (trifluoroethyl) amine | SCIENCE UNION ET CIE (FR) | 1982-02-09 | — | — | US | disclosed |
| US-4267345-A | 2-//PYRROL-2-YL, THIEN-2-YL, OR FUR-2-YL/-ALPHA-TRIFLUOROALKYL-AMINOOXAZOLINES; HYPOTENSIVE AGENTS | SCIENCE UNION ET CIE (FR) | 1981-05-12 | — | — | US | disclosed |