Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.30 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.30 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.30 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.30 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.30 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30871925 | 1.00 | TDP1 (0.35) | TDP1CYP3A4MAPTAGXTTUBB4A | |
| SCHEMBL2231363 | 0.80 | TDP1 (0.40) | TDP1CYP3A4MAPTKDM4EKMO | |
| SCHEMBL13064175 | 0.80 | AGXT (0.33) | AGXT | |
| SCHEMBL7199405 | 0.78 | ALDH1A1 (0.39) | MAPTAGXT | |
| SCHEMBL27960540 | 0.78 | TDP1 (0.39) | TDP1CYP3A4MAPTKDM4EKMO | |
| SCHEMBL29415107 | 0.78 | TDP1 (0.39) | TDP1CYP3A4MAPTKDM4EKMO | |
| SCHEMBL27880131 | 0.78 | TDP1 (0.39) | TDP1CYP3A4MAPTKDM4EKMO | |
| SCHEMBL1660315 | 0.78 | AGXT (0.33) | TDP1CYP3A4MAPTAGXTKDM4E | |
| SCHEMBL13019609 | 0.76 | AGXT (0.30) | AGXT | |
| SCHEMBL12348218 | 0.72 | TDP1 (0.34) | TDP1CYP3A4MAPTKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668140-A | INSECTICIDE, ACARICIDE, NEMATOCIDE, FUNGICIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-16 | — | — | US | disclosed |
| EP-0519211-A1 | Substituted 4-aminopyrimidine, process for their preparation and their use as parasiticide | Hoechst Schering AgrEvo GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |