Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889868 | 0.89 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1USP2NPSR1SMPD1 | |
| SCHEMBL8889931 | 0.87 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1USP2NPSR1SMPD1 | |
| SCHEMBL2034752 | 0.87 | BRD4 (0.51) | ALDH1A1L3MBTL1USP2NPSR1SMPD1 | |
| SCHEMBL8891644 | 0.85 | MAPT (0.60) | ALDH1A1SMPD1MEN1KMT2AHDAC1 | |
| SCHEMBL2188210 | 0.84 | SMPD1 (0.76) | ALDH1A1SMPD1MEN1KMT2AKDM4E | |
| SCHEMBL23317129 | 0.83 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1USP2NPSR1SMPD1 | |
| SCHEMBL2035674 | 0.83 | KMT2A (0.55) | ALDH1A1L3MBTL1USP2NPSR1MEN1 | |
| SCHEMBL24195859 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMPD1MEN1KMT2AKDM4E | |
| SCHEMBL8891197 | 0.82 | PDE4D (0.69) | ALDH1A1L3MBTL1USP2NPSR1SMPD1 | |
| SCHEMBL12112526 | 0.81 | SMN1; SMN2 (0.58) | ALDH1A1L3MBTL1USP2NPSR1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |