Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358848 | 0.80 | SNRNP200 (0.51) | MAPK14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9080839 | 0.79 | DRD4 (0.55) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL8915218 | 0.72 | FFAR4 (0.46) | FFAR4NPC1RAB9AMRGPRX4MCHR1 | |
| SCHEMBL3143366 | 0.71 | FFAR4 (0.44) | FFAR4MAPK14NPC1RAB9AMAPK1 | |
| SCHEMBL3135075 | 0.71 | FFAR4 (0.44) | FFAR4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11527905 | 0.70 | CYP3A4 (0.45) | CYP3A4MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1101974 | 0.70 | MC4R (0.53) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| Hydrochloric Acid SCHEMBL8888785 | 0.69 | HTR1A (0.61) | FFAR4MRGPRX4 | |
| SCHEMBL13144443 | 0.69 | MRGPRX4 (0.68) | FFAR4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4720449 | 0.68 | MAPK14 (0.52) | MAPK14MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652242-A | 3-METHYL-4-(4-(4-(4-PYRIDYL)PIPERAZIN-1-YL)PHENOXY)BURYIC ACID, AMIDE OR ESTER; INHIBITORS OF BINDING OF FIBRINOGEN TO GLYCOPROTEIN | ZENECA LIMITED (GB) | 1997-07-29 | — | — | US | disclosed |
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |