Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 2/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890735 | 0.87 | EGFR (0.63) | EGFRACP1PDE5AABCG2MEN1 | |
| Hydrochloric Acid SCHEMBL8888779 | 0.86 | EGFR (0.62) | EGFRACP1PDE5AABCG2MEN1 | |
| SCHEMBL4740823 | 0.80 | PDE5A (0.72) | EGFRPDE5AABCG2MEN1KMT2A | |
| SCHEMBL6218711 | 0.76 | EGFR (0.70) | EGFRKDRABCG2ERBB2MEN1 | |
| SCHEMBL8893267 | 0.75 | NPY5R (0.60) | EGFRKDM1ANPC1 | |
| Hydrochloric Acid SCHEMBL8909035 | 0.74 | NPY5R (0.59) | EGFRKDM1ANPC1 | |
| SCHEMBL8890043 | 0.72 | PDE3B (0.47) | EGFRKDRMAPTKDM1AKDM4E | |
| SCHEMBL19261422 | 0.70 | PDE5A (0.70) | EGFRPDE5AABCG2MEN1KMT2A | |
| SCHEMBL28092379 | 0.69 | MAPT (0.69) | EGFRKDRPDE5AABCG2MEN1 | |
| SCHEMBL8900475 | 0.69 | EGFR (0.56) | EGFRKDRPDE5AABCG2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |