Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.53 |
| ▸ | PDE5A | O76074 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899361 | 0.86 | ABCG2 (0.67) | EGFRABCG2MEN1KMT2AABCB1 | |
| SCHEMBL3117695 | 0.86 | ABCG2 (0.71) | EGFRABCG2MEN1KMT2AABCB1 | |
| Hydrochloric Acid SCHEMBL8901559 | 0.85 | ABCG2 (0.65) | EGFRABCG2MEN1KMT2AABCB1 | |
| SCHEMBL6039347 | 0.83 | EGFR (0.65) | EGFRABCG2MEN1KMT2AKDR | |
| SCHEMBL6668347 | 0.81 | FBP1 (0.76) | EGFRABCG2MEN1KMT2AABCB1 | |
| SCHEMBL18292473 | 0.80 | EGFR (0.84) | EGFRABCG2MEN1KMT2AFBP1 | |
| SCHEMBL26565406 | 0.78 | PRNP (0.56) | MEN1KMT2A | |
| SCHEMBL8891806 | 0.77 | EGFR (0.64) | EGFRABCG2MEN1KMT2AABCB1 | |
| SCHEMBL20119696 | 0.77 | TTBK1 (0.51) | EGFRABCG2MEN1KMT2AABCB1 | |
| SCHEMBL18895189 | 0.76 | KDM4E (0.65) | EGFRABCG2MEN1KMT2APDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |