Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889671 | 1.00 | MAOB (0.48) | MAOBMIFATMMEN1KMT2A | |
| SCHEMBL8462118 | 0.85 | MAPT (0.53) | MAOBATMMEN1KMT2AALDH1A1 | |
| SCHEMBL8462121 | 0.85 | MAPT (0.53) | MAOBATMMEN1KMT2AALDH1A1 | |
| SCHEMBL8465615 | 0.85 | MAOB (0.49) | MAOBMIFATMMEN1KMT2A | |
| SCHEMBL8465620 | 0.85 | MAOB (0.49) | MAOBMIFATMMEN1KMT2A | |
| SCHEMBL8039511 | 0.83 | MAOB (0.48) | MAOBMIFATMALDH1A1MAPT | |
| SCHEMBL8039514 | 0.83 | MAOB (0.48) | MAOBMIFATMALDH1A1MAPT | |
| SCHEMBL9661080 | 0.78 | MAOB (0.50) | MAOBMIFMAOA | |
| SCHEMBL9661085 | 0.78 | MAOB (0.50) | MAOBMIFMAOA | |
| SCHEMBL8034968 | 0.76 | MAOB (0.57) | MAOBMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641789-A | INHIBITORS OF LEUKOTRIENES AND/OR BLOCKERS OF LEUKOTRIENE RECEPTORS; USEFUL IN PREVENTION OR TREATMENT OF ASTHMA, ARTHRITIS, PSORIASIS, ULCERS, MYOCARDIAL INFARCTION | PFIZER INC. (US) | 1997-06-24 | — | — | US | disclosed |