Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 4/20 | 0.68 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.52 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8908790 | 0.99 | SLC6A1 (0.67) | SLC6A1SLC6A11CHRM1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8885356 | 0.99 | SLC6A1 (0.67) | SLC6A1SLC6A11CHRM1DRD2DRD4 | |
| SCHEMBL8196291 | 0.89 | TSHR (0.54) | SLC6A1CHRM1DRD2DRD4DRD3 | |
| SCHEMBL7611104 | 0.88 | SLC6A1 (0.81) | SLC6A1 | |
| SCHEMBL7607370 | 0.88 | SLC6A1 (0.81) | SLC6A1 | |
| Hydrochloric Acid SCHEMBL8205057 | 0.87 | SLC6A1 (0.80) | SLC6A1 | |
| Hydrochloric Acid SCHEMBL8194496 | 0.87 | SLC6A1 (0.80) | SLC6A1 | |
| SCHEMBL7605625 | 0.86 | SLC6A1 (0.81) | SLC6A1 | |
| SCHEMBL7635294 | 0.86 | SLC6A1 (0.68) | SLC6A1CHRM1DRD2DRD4DRD3 | |
| SCHEMBL7608478 | 0.86 | SLC6A1 (0.68) | SLC6A1CHRM1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595989-A | ANTIINFLAMMATORY AGENTS AND ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 1997-01-21 | — | — | US | claimed |