Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.56 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889592 | 0.99 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2PPARDCA1CA2 | |
| SCHEMBL8889705 | 0.99 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2PPARDCA1CA2 | |
| SCHEMBL8888199 | 0.85 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2 | |
| SCHEMBL8888465 | 0.85 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2 | |
| SCHEMBL8888459 | 0.85 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2 | |
| SCHEMBL8888621 | 0.81 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2 | |
| SCHEMBL8888630 | 0.81 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2 | |
| SCHEMBL8889330 | 0.80 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2 | |
| SCHEMBL8899909 | 0.79 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2 | |
| SCHEMBL8897640 | 0.79 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641789-A | INHIBITORS OF LEUKOTRIENES AND/OR BLOCKERS OF LEUKOTRIENE RECEPTORS; USEFUL IN PREVENTION OR TREATMENT OF ASTHMA, ARTHRITIS, PSORIASIS, ULCERS, MYOCARDIAL INFARCTION | PFIZER INC. (US) | 1997-06-24 | — | — | US | disclosed |