SCHEMBL8889865

SCHEMBL8889865

O=C1c2c(O)c(O)c(O)c(Br)c2C(=O)c2c(O)c(O)c(O)c(Br)c21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACLY P53396 1/20 0.43
CA1 P00915 4/20 0.40
CA2 P00918 4/20 0.40
CA4 P22748 3/20 0.40
CA6 P23280 3/20 0.40
ALDH1A1 P00352 5/20 0.34
HPGD P15428 5/20 0.34
ALOX15 P16050 4/20 0.34
HSD17B10 Q99714 4/20 0.34
MAPT P10636 4/20 0.34
KDM4E B2RXH2 3/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
HIF1A Q16665 2/20 0.34
CYP3A4 P08684 2/20 0.34
ALOX12 P18054 2/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1560273 0.82 MAPT (0.43) ALDH1A1HPGDALOX15HSD17B10MAPT
SCHEMBL11747307 0.72 MEN1 (0.55) ACLYALDH1A1HPGDALOX15HSD17B10
SCHEMBL24727166 0.72 CA1 (0.53) CA1CA2CA4CA6ALDH1A1
SCHEMBL24727403 0.72 CA1 (0.53) CA1CA2CA4CA6ALDH1A1
SCHEMBL9641503 0.69 MAPT (0.53) ALDH1A1HPGDALOX15HSD17B10MAPT
SCHEMBL31467752 0.69 MAPT (0.53) ALDH1A1HPGDALOX15HSD17B10MAPT
SCHEMBL24727059 0.69 CA1 (0.50) CA1CA2CA4CA6ALDH1A1
SCHEMBL28872661 0.69 ALDH1A1 (0.42) ACLYCA1CA2CA4CA6
SCHEMBL29883834 0.69 ALDH1A1 (0.42) ACLYCA1CA2CA4CA6
SCHEMBL18733082 0.67 CA1 (0.67) CA1CA2CA4CA6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997007790-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF INFECTIOUS DISEASES INTERLAB CORPORATION (US) 1997-03-06 WO disclosed