Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 6/20 | 0.36 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 5/20 | 0.36 |
| ▸ | MMP8 | P22894 | 4/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872944 | 0.81 | MMP2 (0.57) | ANPEPDNPEPMMP2MMP8MMP9 | |
| SCHEMBL8872951 | 0.81 | MMP2 (0.57) | ANPEPDNPEPMMP2MMP8MMP9 | |
| SCHEMBL15980616 | 0.80 | SLC1A3 (0.43) | SLC7A5ALDH1A1TSHRMAPK1ANPEP | |
| SCHEMBL15980617 | 0.80 | SLC1A3 (0.43) | SLC7A5ALDH1A1TSHRMAPK1ANPEP | |
| SCHEMBL3686597 | 0.80 | SLC1A3 (0.43) | SLC7A5ALDH1A1TSHRMAPK1ANPEP | |
| SCHEMBL11467290 | 0.76 | ANPEP (0.53) | SLC7A5ALDH1A1TSHRMAPK1ANPEP | |
| SCHEMBL8871238 | 0.74 | SLC7A5 (0.48) | SLC7A5ALDH1A1ANPEPRNPEPCACNA2D1 | |
| SCHEMBL12015470 | 0.74 | ACE (0.38) | SLC7A5ALDH1A1TSHRMAPK1ANPEP | |
| SCHEMBL664075 | 0.74 | SLC7A5 (0.48) | SLC7A5ALDH1A1ANPEPRNPEPCACNA2D1 | |
| Hydrochloric Acid SCHEMBL9515723 | 0.74 | ANPEP (0.52) | SLC7A5ALDH1A1TSHRMAPK1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003966-A1 | N-(AMINO ACID) SUBSTITUTED SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-02-06 | — | — | WO | claimed |