Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | IL18 | Q14116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889350 | 0.84 | IDO1 (0.46) | NAMPTSAE1UBA2MAPTKMT2A | |
| SCHEMBL19749 | 0.80 | ELANE (0.47) | ALDH1A1TSHRHTTKDM4EPOLB | |
| SCHEMBL18993409 | 0.80 | ELANE (0.41) | NAMPTMAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL752964 | 0.77 | NAMPT (0.48) | NAMPTSAE1UBA2MAPTKMT2A | |
| SCHEMBL18010125 | 0.76 | AKR1C3 (0.39) | NAMPTMAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL16692702 | 0.76 | ELANE (0.38) | NAMPTMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL18184936 | 0.76 | CYP19A1 (0.56) | NAMPTSAE1UBA2MAPTKMT2A | |
| SCHEMBL17276579 | 0.73 | RAB9A (0.51) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL15016132 | 0.72 | RAB9A (0.54) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL3700860 | 0.71 | NAMPT (0.58) | NAMPTSAE1UBA2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003976-A1 | SEMICARBAZONE DERIVATIVES AND PESTICIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |