Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636124 | 0.78 | ALDH1A1 (0.59) | SMN1; SMN2TDP1KMT2AMEN1POLB | |
| SCHEMBL1155564 | 0.78 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1KDM4EUSP2 | |
| SCHEMBL14880879 | 0.78 | HPGD (0.47) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL31456325 | 0.77 | POLB (0.67) | SMN1; SMN2TDP1KMT2AMEN1POLB | |
| SCHEMBL10594113 | 0.77 | ALDH1A1 (0.66) | SMN1; SMN2TDP1KMT2AMEN1POLB | |
| SCHEMBL3363014 | 0.77 | MEN1 (0.54) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10762419 | 0.76 | MEN1 (0.57) | SMN1; SMN2TDP1KMT2AMEN1POLB | |
| Ethyl Acetate SCHEMBL28704417 | 0.74 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBALDH1A1KDM4EGAA | |
| SCHEMBL10570773 | 0.74 | SMN1; SMN2 (0.70) | SMN1; SMN2TDP1KMT2AMEN1POLB | |
| SCHEMBL3042045 | 0.74 | POLB (0.62) | SMN1; SMN2TDP1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |