Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.64 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.60 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406524 | 0.92 | PPARD (0.59) | PPARDCYSLTR2CYSLTR1TSHRPTGDR2 | |
| SCHEMBL2225179 | 0.90 | LMNA (0.57) | PPARDCYSLTR2CYSLTR1TSHRPTGDR2 | |
| SCHEMBL9364600 | 0.88 | MEN1 (0.70) | PPARDCYSLTR2CYSLTR1TSHRPTGDR2 | |
| SCHEMBL29184830 | 0.87 | MAOB (0.70) | PPARDMAPTCYP2C9PPARGL3MBTL1 | |
| SCHEMBL7404901 | 0.85 | MCL1 (0.64) | PPARDCYSLTR2CYSLTR1TSHRPTGDR2 | |
| SCHEMBL18791370 | 0.85 | PTGDR2 (0.56) | PPARDCYSLTR2CYSLTR1TSHRPTGDR2 | |
| SCHEMBL10648853 | 0.83 | PTGDR2 (0.55) | PPARDCYSLTR2CYSLTR1TSHRPTGDR2 | |
| SCHEMBL1530794 | 0.83 | PTGDR2 (0.77) | PPARDCYSLTR2CYSLTR1TSHRPTGDR2 | |
| SCHEMBL12238280 | 0.83 | PPARD (0.61) | PPARDCYSLTR2CYSLTR1TSHRPTGDR2 | |
| SCHEMBL670821 | 0.83 | PPARD (0.61) | PPARDCYSLTR2CYSLTR1TSHRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652242-A | 3-METHYL-4-(4-(4-(4-PYRIDYL)PIPERAZIN-1-YL)PHENOXY)BURYIC ACID, AMIDE OR ESTER; INHIBITORS OF BINDING OF FIBRINOGEN TO GLYCOPROTEIN | ZENECA LIMITED (GB) | 1997-07-29 | — | — | US | disclosed |