⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL5369986 | 0.98 | BAZ2B (0.53) | — | |
| SCHEMBL27945452 | 0.98 | BAZ2B (0.53) | — | |
| SCHEMBL27853139 | 0.98 | BAZ2B (0.53) | — | |
| SCHEMBL889025 | 0.82 | — | — | |
| SCHEMBL28164192 | 0.80 | BAZ2B (0.39) | — | |
| SCHEMBL759817 | 0.80 | — | — | |
| SCHEMBL19913401 | 0.77 | BAZ2B (0.50) | — | |
| SCHEMBL18415312 | 0.77 | BAZ2B (0.50) | — | |
| SCHEMBL4251404 | 0.77 | MMP2 (0.50) | — | |
| SCHEMBL19296762 | 0.77 | BAZ2B (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167944-B | Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors | 联合疗法公司 | 2024-08-23 | — | — | CN | claimed |
| CN-116870191-A | Preparation method and application of drug-loaded zeolite imidazole salt framework nano-particles | 常州大学 | 2023-10-13 | — | — | CN | claimed |
| CN-105418593-A | Preparation method of key intermediate of olmesartan medoxomil and olmesartan medoxomil | BENGBU BBCA TUSHAN PHARM CO | 2016-03-23 | — | — | CN | claimed |
| CN-103435602-A | Preparation method of olmesartan medoxomil | INST OF MATERIA MEDICA SHANDONG ACADEMY OF MEDICAL SCIENCES | 2013-12-11 | — | — | CN | claimed |
| CN-102351849-A | Preparation method of olmesartan medoxomil | QILU TIANHE PHARMACEUTICAL CO LTD | 2012-02-15 | — | — | CN | claimed |
| WO-2007148344-A2 | PROCESS FOR THE PREPARATION OF OLMESARTAN MEDOXOMIL | MATRIX LABORATORIES LIMITED (IN) | 2007-12-27 | — | — | WO | claimed |
| CN-1045770-C | Process for preparing 1-biphenylmethylimidazole derivatives | SANKYO CO (JP) | 1999-10-20 | — | — | CN | claimed |
| CN-1085896-A | The Angiotensin II antagonist imidazole derivatives, their preparation and therepic use thereof | SANKYO CO (JP) | 1994-04-27 | — | — | CN | claimed |
| US-20250388585-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2025-12-25 | — | — | US | disclosed |
| US-12448388-B2 | PRMT5 inhibitors and uses thereof | GILEAD SCIENCES, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| US-20240376110-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. | 2024-11-14 | — | — | US | disclosed |
| WO-2024220917-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| CN-110167944-B | Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors | 联合疗法公司 | 2024-08-23 | — | — | CN | disclosed |
| WO-2024076155-A1 | NOVEL COMPOUND AS YEATS DOMAIN INHIBITOR | 노보렉스 주식회사 | 2024-04-11 | — | — | WO | disclosed |
| US-5811445-A | ANGIOTENSIN II INHIBITORS | ROUSSEL UCLAF (FR) | 1998-09-22 | — | — | US | disclosed |
| CN-1189490-A | Process for preparing 1-biphenylmethylimidazole derivatives | SANKYO CO (JP) | 1998-08-05 | — | — | CN | disclosed |
| WO-1997016192-A1 | MUSCARINE ANTAGONISTS | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | disclosed |
| EP-0742200-A1 | Manufacturing method of sulphides | KONICA CORPORATION (JP) | 1996-11-13 | — | — | EP | disclosed |
| CN-1085896-A | The Angiotensin II antagonist imidazole derivatives, their preparation and therepic use thereof | SANKYO CO (JP) | 1994-04-27 | — | — | CN | disclosed |
| CN-1071426-A | The preparation method of the new acetal of imidazole-5-carboxylic acid derivant | CHEM PHARM FORSCH GMBH (AT) | 1993-04-28 | — | — | CN | disclosed |