Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | SELE | P16581 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885373 | 1.00 | THRB (0.49) | THRBTHRASMN1; SMN2MAPTPLA2G4A | |
| SCHEMBL8884217 | 1.00 | THRB (0.49) | THRBTHRASMN1; SMN2MAPTPLA2G4A | |
| SCHEMBL8769272 | 1.00 | THRB (0.49) | THRBTHRASMN1; SMN2MAPTPLA2G4A | |
| SCHEMBL7164023 | 1.00 | THRB (0.49) | THRBTHRASMN1; SMN2MAPTPLA2G4A | |
| SCHEMBL8882011 | 1.00 | THRB (0.49) | THRBTHRASMN1; SMN2MAPTPLA2G4A | |
| SCHEMBL8886085 | 0.98 | THRB (0.46) | THRBTHRASMN1; SMN2MAPTPLA2G4A | |
| SCHEMBL8768333 | 0.98 | THRB (0.49) | THRBTHRASMN1; SMN2MAPTPLA2G4A | |
| SCHEMBL8768339 | 0.98 | THRB (0.46) | THRBTHRASMN1; SMN2MAPTPLA2G4A | |
| SCHEMBL8546213 | 0.94 | THRB (0.46) | THRBTHRASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8769317 | 0.93 | THRB (0.44) | THRBTHRASMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595685-A | THIAZOLE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0439170-B1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KK (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0439170-A2 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KABUSHIKI KAISHA (JP) | 1991-07-31 | — | — | EP | disclosed |