Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 11/20 | 0.63 |
| ▸ | NPY1R | P25929 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | AQP1 | P29972 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | NPY4R | P50391 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888802 | 0.87 | NPY5R (0.64) | NPY5RNPY1RALDH1A1HPGDADRA2A | |
| SCHEMBL8898918 | 0.86 | NPY5R (0.62) | NPY5RNPY1RALDH1A1HPGDADRA2A | |
| SCHEMBL8889955 | 0.86 | NPY5R (0.66) | NPY5RNPY1RALDH1A1HPGDADRA2A | |
| SCHEMBL8889950 | 0.86 | NPY5R (0.66) | NPY5RNPY1RALDH1A1HPGDADRA2A | |
| SCHEMBL4390192 | 0.82 | NPY5R (0.67) | NPY5RNPY1RALDH1A1HPGDADRA2A | |
| SCHEMBL4007555 | 0.82 | NPY5R (0.67) | NPY5RNPY1RALDH1A1HPGDADRA2A | |
| SCHEMBL14606719 | 0.80 | NPY5R (0.64) | NPY5RNPY1RALDH1A1HPGDADRA2A | |
| SCHEMBL5774740 | 0.80 | NPY5R (0.64) | NPY5RNPY1RALDH1A1HPGDADRA2A | |
| SCHEMBL5126972 | 0.80 | NPY5R (0.64) | NPY5RNPY1RALDH1A1HPGDADRA2A | |
| SCHEMBL6039411 | 0.79 | ACACB (0.69) | NPY5RNPY1RALDH1A1HPGDADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |