Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 12/20 | 0.67 |
| ▸ | NPY1R | P25929 | 4/20 | 0.64 |
| ▸ | AQP1 | P29972 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | NPY2R | P49146 | 1/20 | 0.60 |
| ▸ | NPY4R | P50391 | 1/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | GBA1 | P04062 | 2/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007555 | 1.00 | NPY5R (0.67) | NPY5RNPY1RAQP1ALDH1A1ADRA2A | |
| SCHEMBL8888802 | 0.88 | NPY5R (0.64) | NPY5RNPY1RAQP1ALDH1A1ADRA2A | |
| SCHEMBL13796481 | 0.86 | NPY5R (0.62) | NPY5RNPY1RAQP1ALDH1A1ADRA2A | |
| SCHEMBL4394901 | 0.86 | PRKD3 (0.55) | NPY5RNPY1RAQP1ALDH1A1ADRA2A | |
| SCHEMBL4394897 | 0.86 | PRKD3 (0.55) | NPY5RNPY1RAQP1ALDH1A1ADRA2A | |
| SCHEMBL8898918 | 0.84 | NPY5R (0.62) | NPY5RNPY1RAQP1ALDH1A1ADRA2A | |
| SCHEMBL8889955 | 0.84 | NPY5R (0.66) | NPY5RNPY1RAQP1ALDH1A1ADRA2A | |
| SCHEMBL8889950 | 0.84 | NPY5R (0.66) | NPY5RNPY1RAQP1ALDH1A1ADRA2A | |
| SCHEMBL6039406 | 0.84 | ACACB (0.69) | NPY5RNPY1RAQP1ALDH1A1ADRA2A | |
| SCHEMBL6039411 | 0.84 | ACACB (0.69) | NPY5RNPY1RAQP1ALDH1A1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | claimed |
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ACACA, ACACB, ACAT1 | NPY5R 890/4885NPY1R 1288/4885AQP1 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.