Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 15/20 | 0.73 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | MERTK | Q12866 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900188 | 0.94 | NPY5R (0.80) | NPY5RMERTKADRA2AAPPBCHE | |
| SCHEMBL8900185 | 0.94 | NPY5R (0.80) | NPY5RMERTKADRA2AAPPBCHE | |
| SCHEMBL8911038 | 0.83 | NPY5R (1.00) | NPY5RMERTKADRA2AAPPBCHE | |
| SCHEMBL8891621 | 0.83 | NPY5R (1.00) | NPY5RCAMK2DSOS1MERTKAPP | |
| Hydrochloric Acid SCHEMBL8901600 | 0.82 | NPY5R (0.98) | NPY5RMERTKADRA2AAPPBCHE | |
| SCHEMBL8890847 | 0.81 | NPY5R (0.61) | NPY5RMERTKADRA2AAPPBCHE | |
| SCHEMBL8890851 | 0.81 | NPY5R (0.61) | NPY5RMERTKADRA2AAPPBCHE | |
| SCHEMBL8890740 | 0.81 | NPY5R (1.00) | NPY5RCAMK2DMERTKADRA2AAPP | |
| SCHEMBL8891244 | 0.80 | NPY5R (1.00) | NPY5RSOS1MERTKADRA2AAPP | |
| SCHEMBL8891052 | 0.80 | NPY5R (1.00) | NPY5RCAMK2DMERTKADRA2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |