Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 11/20 | 1.00 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.47 |
| ▸ | TCF7L2 | Q9NQB0 | 3/20 | 0.47 |
| ▸ | MERTK | Q12866 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891052 | 0.91 | NPY5R (1.00) | NPY5RCAMK2DCTNNB1TCF7L2MERTK | |
| SCHEMBL8891621 | 0.85 | NPY5R (1.00) | NPY5RCAMK2DCTNNB1TCF7L2MERTK | |
| SCHEMBL8890729 | 0.82 | NPY5R (0.72) | NPY5RCAMK2DCTNNB1TCF7L2MERTK | |
| SCHEMBL8890766 | 0.82 | NPY5R (0.72) | NPY5RCAMK2DCTNNB1TCF7L2MERTK | |
| SCHEMBL8891617 | 0.81 | NPY5R (0.71) | NPY5RCTNNB1TCF7L2MERTKAPP | |
| SCHEMBL8891632 | 0.81 | NPY5R (0.71) | NPY5RCTNNB1TCF7L2MERTKAPP | |
| SCHEMBL8890575 | 0.81 | NPY5R (0.73) | NPY5RCAMK2DMERTKADRA2AMCHR1 | |
| SCHEMBL8891244 | 0.81 | NPY5R (1.00) | NPY5RCTNNB1TCF7L2MERTKADRA2A | |
| SCHEMBL8891045 | 0.80 | NPY5R (0.68) | NPY5RCTNNB1TCF7L2MERTKAPP | |
| SCHEMBL8891065 | 0.80 | NPY5R (0.68) | NPY5RCTNNB1TCF7L2MERTKAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |