Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.62 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.62 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890683 | 1.00 | ALOX5 (0.65) | ALOX5FFAR1AKR1B1GPBAR1CYSLTR1 | |
| SCHEMBL8890270 | 0.99 | ALOX5 (0.64) | ALOX5FFAR1AKR1B1GPBAR1CYSLTR1 | |
| SCHEMBL8890256 | 0.99 | ALOX5 (0.64) | ALOX5FFAR1AKR1B1GPBAR1CYSLTR1 | |
| SCHEMBL1419872 | 0.85 | FFAR1 (0.77) | ALOX5FFAR1AKR1B1GPBAR1CYSLTR1 | |
| SCHEMBL7594868 | 0.84 | GPBAR1 (0.60) | ALOX5FFAR1AKR1B1GPBAR1CYSLTR1 | |
| SCHEMBL7594851 | 0.84 | GPBAR1 (0.60) | ALOX5FFAR1AKR1B1GPBAR1CYSLTR1 | |
| SCHEMBL7594542 | 0.83 | GPBAR1 (0.59) | ALOX5FFAR1AKR1B1GPBAR1CYSLTR1 | |
| SCHEMBL7594522 | 0.83 | GPBAR1 (0.59) | ALOX5FFAR1AKR1B1GPBAR1CYSLTR1 | |
| SCHEMBL13772730 | 0.82 | GPBAR1 (0.70) | ALOX5FFAR1AKR1B1GPBAR1CYSLTR1 | |
| SCHEMBL1419915 | 0.82 | ALOX5 (0.72) | ALOX5FFAR1AKR1B1GPBAR1CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997012866-A1 | BIS-HETEROARYLYLMETHOXYPHENYLKETONE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-04-10 | — | — | WO | disclosed |