Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.64 |
| ▸ | NSD2 | O96028 | 7/20 | 0.57 |
| ▸ | SCN1A | P35498 | 2/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457681 | 0.90 | NPY5R (0.64) | NPY5RNSD2SCN1ASCN2ASCN3A | |
| SCHEMBL20026077 | 0.85 | NSD2 (0.70) | NPY5RNSD2SCN1ASCN2ASCN3A | |
| SCHEMBL5663391 | 0.85 | KMT2A (0.66) | NPY5RNSD2CYP3A4 | |
| SCHEMBL6006634 | 0.80 | CYP3A4 (0.69) | NPY5RNSD2SCN1ASCN2ASCN3A | |
| SCHEMBL8900540 | 0.78 | NPY5R (0.53) | NPY5RNSD2CYP19A1CA1 | |
| Hydrochloric Acid SCHEMBL8889419 | 0.78 | NPY5R (0.98) | NPY5RNSD2ALDH1A1 | |
| SCHEMBL4487552 | 0.77 | NSD2 (0.63) | NPY5RNSD2ALDH1A1CYP19A1CA9 | |
| SCHEMBL14434572 | 0.76 | CNR1 (0.52) | NPY5RNSD2SCN1ASCN2ASCN3A | |
| SCHEMBL4263470 | 0.76 | CYP3A4 (0.78) | NPY5RNSD2SCN1ASCN2ASCN3A | |
| Hydrochloric Acid SCHEMBL4493664 | 0.76 | NSD2 (0.64) | NPY5RNSD2SCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |