Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.53 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890903 | 1.00 | NPY5R (0.53) | NPY5RPDE5AAPPBCHEACHE | |
| SCHEMBL8911032 | 0.85 | NPY5R (0.68) | NPY5RPDE5AAPPBCHEACHE | |
| SCHEMBL8911051 | 0.85 | NPY5R (0.68) | NPY5RPDE5AAPPBCHEACHE | |
| SCHEMBL8890906 | 0.85 | NPY5R (0.75) | NPY5RAPPBCHEACHE | |
| Hydrochloric Acid SCHEMBL8901595 | 0.84 | NPY5R (0.67) | NPY5RPDE5AAPPBCHEACHE | |
| Hydrochloric Acid SCHEMBL8901613 | 0.84 | NPY5R (0.67) | NPY5RPDE5AAPPBCHEACHE | |
| SCHEMBL8890845 | 0.83 | NPY5R (0.52) | NPY5RAPPBCHEACHEMERTK | |
| SCHEMBL8890851 | 0.83 | NPY5R (0.61) | NPY5RAPPBCHEACHEMERTK | |
| SCHEMBL8890847 | 0.83 | NPY5R (0.61) | NPY5RAPPBCHEACHEMERTK | |
| SCHEMBL8901670 | 0.82 | NPY5R (0.65) | NPY5RMERTKPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |