Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.65 |
| ▸ | MERTK | Q12866 | 3/20 | 0.52 |
| ▸ | GALR2 | O43603 | 1/20 | 0.51 |
| ▸ | GALR1 | P47211 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | PAK4 | O96013 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8892514 | 0.99 | NPY5R (0.64) | NPY5RMERTKGALR2GALR1AURKA | |
| SCHEMBL8890639 | 0.91 | MERTK (0.63) | NPY5RMERTKGSK3AGSK3BCCR4 | |
| Hydrochloric Acid SCHEMBL8901180 | 0.90 | MERTK (0.62) | NPY5RMERTKGSK3AGSK3BCCR4 | |
| SCHEMBL8890906 | 0.82 | NPY5R (0.75) | NPY5R | |
| SCHEMBL8890903 | 0.82 | NPY5R (0.53) | NPY5RMERTKPDGFRA | |
| SCHEMBL8890913 | 0.82 | NPY5R (0.53) | NPY5RMERTKPDGFRA | |
| SCHEMBL8890851 | 0.81 | NPY5R (0.61) | NPY5RMERTK | |
| SCHEMBL8890847 | 0.81 | NPY5R (0.61) | NPY5RMERTK | |
| SCHEMBL8890845 | 0.81 | NPY5R (0.52) | NPY5RMERTK | |
| SCHEMBL8899277 | 0.80 | NPY5R (1.00) | NPY5RMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |