Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890981 | 0.84 | APP (0.45) | APPCACNA2D1NPC1PKMRAB9A | |
| SCHEMBL8892545 | 0.77 | NPY5R (0.70) | APPNPC1PKMRAB9ANFKB1 | |
| SCHEMBL6039582 | 0.77 | NPY5R (0.70) | APPNPC1PKMRAB9ANFKB1 | |
| SCHEMBL8893524 | 0.77 | NPY5R (0.70) | APPNPC1PKMRAB9ANFKB1 | |
| SCHEMBL8890573 | 0.76 | APP (0.56) | APPNPC1PKMRAB9ANFKB1 | |
| Hydrochloric Acid SCHEMBL8892586 | 0.76 | NPY5R (0.68) | APPNPC1PKMRAB9ANFKB1 | |
| SCHEMBL8891300 | 0.74 | APP (0.60) | APPNPC1PKMRAB9ANFKB1 | |
| SCHEMBL8892745 | 0.70 | APP (0.45) | APPNPC1PKMRAB9ANFKB1 | |
| SCHEMBL8891067 | 0.69 | NPY5R (0.45) | APPNPC1PKMRAB9ANFKB1 | |
| SCHEMBL8890944 | 0.69 | APP (0.45) | APPNPC1PKMRAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020821-A1 | HETEROARYL DERIVATIVES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |