Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.45 |
| ▸ | AQP1 | P29972 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8901432 | 0.99 | NPC1 (0.45) | NPY5RAQP1ALDH1A1ADRA2AMAPT | |
| SCHEMBL8893962 | 0.84 | NPY5R (0.50) | NPY5R | |
| SCHEMBL8891058 | 0.81 | NPY5R (0.41) | NPY5RAQP1ALDH1A1ADRA2AMAPT | |
| Hydrochloric Acid SCHEMBL8901427 | 0.81 | NPC1 (0.43) | NPY5RAQP1ALDH1A1ADRA2AMAPT | |
| SCHEMBL8900899 | 0.79 | NPY5R (0.61) | NPY5RAQP1ALDH1A1ADRA2AMAPT | |
| SCHEMBL2636281 | 0.79 | NPY5R (0.64) | NPY5RAQP1ALDH1A1ADRA2AMAPT | |
| Hydrochloric Acid SCHEMBL8906965 | 0.78 | NPY5R (0.62) | NPY5RAQP1ALDH1A1ADRA2AMAPT | |
| Hydrochloric Acid SCHEMBL2675360 | 0.78 | NPY5R (0.62) | NPY5RAQP1ALDH1A1ADRA2AMAPT | |
| Hydrochloric Acid SCHEMBL8901980 | 0.78 | NPY5R (0.60) | NPY5RAQP1ALDH1A1ADRA2AMAPT | |
| SCHEMBL8892683 | 0.74 | NPY5R (0.60) | NPY5RAQP1ALDH1A1ADRA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |