Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892612 | 0.90 | TBXA2R (0.36) | KMT2AMEN1MDM2MAPTLMNA | |
| SCHEMBL8892485 | 0.85 | MAPT (0.35) | KMT2ANPC1RAB9AMAPK1MAPT | |
| SCHEMBL8890001 | 0.85 | KDM4E (0.36) | KMT2ANPC1RAB9AMAPK1MAPT | |
| SCHEMBL8892121 | 0.85 | TBXA2R (0.36) | NPC1RAB9AMAPK1MAPTLMNA | |
| SCHEMBL8891568 | 0.84 | HPGD (0.36) | KMT2AMEN1NPC1RAB9AMDM2 | |
| SCHEMBL8888828 | 0.82 | KDM4E (0.35) | L3MBTL1NPC1RAB9AMAPK1P2RX7 | |
| SCHEMBL8890372 | 0.81 | FFAR4 (0.36) | SIGMAR1RAB9AMAPT | |
| SCHEMBL8489371 | 0.78 | HPGD (0.50) | KMT2AMEN1NPC1RAB9AMAPK1 | |
| SCHEMBL8907895 | 0.77 | HPGD (0.36) | KMT2AMEN1RAB9AMAPTLMNA | |
| SCHEMBL8892828 | 0.77 | DHODH (0.32) | EPHX2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |